How amikacin sulfate in the treatment of colibacillosis


Escherichia coli is an intestinal disease due to Escherichia coli infection, diarrhea is the main symptom, Escherichia coli is a common bacteria such as human and animal intestinal tract, so people or animals are possible because of diseases caused by Escherichia coli. Amikacin sulfate as an antibiotic, is good for many kinds of fungus or bacteria have resistance, also has a strong activity of Escherichia coli, so it can be used in the treatment of colibacillosis. So how did amikacin sulfate treatment of colibacillosis in? Sulfuric acid Amy brulamycin is a amino Glycoside class antibiotics, on most intestinal Bacillus section bacteria, as colorectal Escherichia coli bacteria, and Crabb bacteria is, and intestinal Bacillus is, and deformation Bacillus is, and records he bacteria is, and salmonella bacteria is, and sildenafil citrate acid Bacillus is, and Shara bacteria is, are with role, on Pseudomonas aeruginosa fake single cell bacteria and the part other fake single cell bacteria, and not moving Bacillus is, and produced alkali Bacillus is, also has role; on meningitis cocci, and got cocci, and flu Bacillus, and Yersinia enterocolitica bacteria is, and fetal bent bacteria, and Mycobacterium tuberculosis and the some points branch Bacillus is also with antibacterial role, The antibacterial activity of gentamicin was slightly lower. So how did amikacin sulfate treatment of colibacillosis in? Test results showed that amikacin sulfate lipid body height, the effect of the dose significantly higher than the control group. The possible reasons are because of the Phospholipid bilayer of liposomes with the bacterial cell wall and cell membrane fusion. Drugs directly into the cell, affected the bacterial protein synthesis and drug better antibacterial effect. Interaction between liposomes and cells as follows: 1, adsorption Because of physical attraction or through receptors that liposomes are cell surface adsorption, hardly cause drug or adsorption of lipids to cell internal transport, but after adsorption-induced cellular uptake of liposomes. 2 release, contact Liposomes through the liposome membrane permeability caused by contact with the cells increases in the water phase of the package release of drugs into cells. The way to introducing drugs to specific cells without having to ingest the entire Liposomes, for those who are not Phagocytic activity of cells, this is a special way to ingest drugs. 3, fusion After the combination of liposomes and membranes, leading to their fusion. To cause complete mixing of Phospholipid and liposome membrane, liposome drug released into the cytoplasm. 4, Endocytosis Liposomes with the main mechanism of the interaction between cells. Liposomes into the body cells as foreign by phagocytosis of reticuloendothelial system after foreign body swallowed and then destroyed by the cells Lysosomes, release drugs for lysosome or other organelle. How amikacin sulfate in the treatment of colibacillosis in? Amikacin sulfate is a drug for treatment of colibacillosis, patients with this disease can take. In daily life, we should pay attention to food hygiene, prevention of colibacillosis.